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CD16 抗体 (FITC)

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in FACS. Suitable for 人.
产品编号 ABIN120565
发货至: 中国

Quick Overview for CD16 抗体 (FITC) (ABIN120565)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-154
  • 特异性

    The antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgRIII antigen). The antibody MEM-154 reacts with CD16+ granulocytes.

    免疫原

    Human granulocytes

    亚型

    IgG1
  • 应用备注

    Flow Cytometry of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade Protease free BSA as a stabilizing agent.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD16

    别名

    CD16

    背景

    CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

    基因ID

    2214

    UniProt

    P08637

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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